Superoxide dismutase activity was elevated in heart and DVL of H rats, and in soleus of L rats ( P < 0.05). Oxidant generation, measured with 2′7′-dichlorofluorescin (DCFH), was significantly lowered with ginseng feeding in the homogenates of heart, soleus, and the deep portion of vastus lateralis muscle (DVL) ( P < 0.05) in both Y and O rats, and the effects were dose dependent. Female Fischer 344 rats at 4 (Y, n = 38) or 22 (O, n = 25) mo of age were randomly divided into three groups and fed either a AIN-93G formula-based control diet (C) or a diet containing 0.5 g/kg (low dose, L) or 2.5 g/kg (high dose, H) dry ginseng power for 4 mo.
The antioxidant properties of North American ginseng ( Panax quinquefolium) were investigated in young and old rats fed a ginseng-supplemented diet for 4 mo.
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